Though she made her screen debut as a child alongside her father Jon Voight in the 1982 film Lookin' to Get Out, Jolie's acting career began in earnest a decade later with the low budget production Cyborg 2 (1993). Her first leading role in a major film was in Hackers (1995). She had her biggest commercial success with the action-comedy Mr. & Mrs. Smith (2005).
Divorced from actors Jonny Lee Miller and Billy Bob Thornton, Jolie currently lives with actor Brad Pitt, in a relationship that has attracted worldwide media attention. Jolie and Pitt have three adopted children, Maddox, Pax, and Zahara, as well as a biological daughter, Shiloh. Jolie has promoted humanitarian causes throughout the world, and is noted for her work with refugees through UNHCR.